Fiber-centered analysis of brain connectivities using DTI and resting state FMRI data

Jinglei Lv, Lei Guo, Xintao Hu, Tuo Zhang, Kaiming Li, Degang Zhang, Jianfei Yang, Tianming Liu

科研成果: 书/报告/会议事项章节会议稿件同行评审

14 引用 (Scopus)

摘要

Recently, inference of functional connectivity between brain regions using resting state fMRI (rsfMRI) data has attracted significant interests in the neuroscience community. This paper proposes a novel fiber-centered approach to study the functional connectivity between brain regions using high spatial resolution diffusion tensor imaging (DTI) and rsfMRI data. We measure the functional coherence of a fiber as the time series' correlation of two gray matter voxels that this fiber connects. The functional connectivity strength between two brain regions is defined as the average functional coherence of fibers connecting them. Our results demonstrate that: 1) The functional coherence of fibers is correlated with the brain regions they connect; 2) The functional connectivity between brain regions is correlated with structural connectivity. And these two patterns are consistent across subjects. These results may provide new insights into the brain's structural and functional architecture.

源语言英语
主期刊名Medical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings
143-150
页数8
版本PART 2
DOI
出版状态已出版 - 2010
活动13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, 中国
期限: 20 9月 201024 9月 2010

出版系列

姓名Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
编号PART 2
6362 LNCS
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
国家/地区中国
Beijing
时期20/09/1024/09/10

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