Photoelectric neural interface combining wire-bonding μleds with iridium oxide microelectrodes for optogenetics

Bo Wen Ji, Xiao Yang Kang, Ming Hao Wang, Bu Feng Bao, Hong Chang Tian, Bin Yang, Xiang Chen, Xiao Lin Wang, Jing Quan Liu

科研成果: 书/报告/会议事项章节会议稿件同行评审

11 引用 (Scopus)

摘要

This paper reports the design, fabrication, electrical and thermal characterization, as well as attachment and stability of a flexible photoelectric neural interface (PENI). Upon the wire-bonding technology, three micro LED (μLED) chips are well-connected to the polyimide substrate as an array, with their luminous surfaces over against the holes. Meanwhile, a Parylene-C-based array with four microelectrodes (200 μm in diameter) modified by sputtering iridium oxide film is fabricated to record micro electrocorticography (μECoG) signals. Then, the back-to-back assembly is utilized to allow blue light through the aligned holes on both arrays with almost no attenuation. As an optogenetics tool, the PENI can be attached on the cortical surface of a mouse expressing ChR2 to realize synchronized light modulating and neural signal recording.

源语言英语
主期刊名2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
出版商Institute of Electrical and Electronics Engineers Inc.
538-541
页数4
ISBN(电子版)9781509050789
DOI
出版状态已出版 - 23 2月 2017
已对外发布
活动30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, 美国
期限: 22 1月 201726 1月 2017

出版系列

姓名Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN(印刷版)1084-6999

会议

会议30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
国家/地区美国
Las Vegas
时期22/01/1726/01/17

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