Detection of thrombin based on the conformational effects of water-soluble conjugated polymer

Xing Fen Liu; Li Hua Wang; Shi Ping Song; Chun Hai Fan; Wei Huang

Detection of thrombin based on the conformational effects of water-soluble conjugated polymer

Xing Fen Liu, Li Hua Wang, Shi Ping Song, Chun Hai Fan, Wei Huang

科研成果: 期刊稿件 › 文章 › 同行评审

1 引用（Scopus）

摘要

We introduce the application of water-soluble conjugated polymers and aptamer in the detection of biomolecules. Then a colorimetric protocol based on aptamer and conformational effects of water-soluble polythio-phene is reported. It is demonstrated that the protein sensor we designed is highly selective and sensitive, and the lowest detection limit with naked eyes is 63 nM.

源语言	英语
页（从-至）	59-63
页数	5
期刊	Nanjing Youdian Daxue Xuebao (Ziran Kexue Ban)/Journal of Nanjing University of Posts and Telecommunications (Natural Science)
卷	28
期	1
出版状态	已出版 - 2月 2008
已对外发布	是

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abstract = "We introduce the application of water-soluble conjugated polymers and aptamer in the detection of biomolecules. Then a colorimetric protocol based on aptamer and conformational effects of water-soluble polythio-phene is reported. It is demonstrated that the protein sensor we designed is highly selective and sensitive, and the lowest detection limit with naked eyes is 63 nM.",

keywords = "Aptamer, Biosensors, Conjugated polymer, Protein, Thrombin",

author = "Liu, {Xing Fen} and Wang, {Li Hua} and Song, {Shi Ping} and Fan, {Chun Hai} and Wei Huang",

year = "2008",

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Detection of thrombin based on the conformational effects of water-soluble conjugated polymer. / Liu, Xing Fen; Wang, Li Hua; Song, Shi Ping 等.
在: Nanjing Youdian Daxue Xuebao (Ziran Kexue Ban)/Journal of Nanjing University of Posts and Telecommunications (Natural Science), 卷 28, 号码 1, 02.2008, 页码 59-63.

科研成果: 期刊稿件 › 文章 › 同行评审

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T1 - Detection of thrombin based on the conformational effects of water-soluble conjugated polymer

AU - Liu, Xing Fen

AU - Wang, Li Hua

AU - Song, Shi Ping

AU - Fan, Chun Hai

AU - Huang, Wei

PY - 2008/2

Y1 - 2008/2

N2 - We introduce the application of water-soluble conjugated polymers and aptamer in the detection of biomolecules. Then a colorimetric protocol based on aptamer and conformational effects of water-soluble polythio-phene is reported. It is demonstrated that the protein sensor we designed is highly selective and sensitive, and the lowest detection limit with naked eyes is 63 nM.

AB - We introduce the application of water-soluble conjugated polymers and aptamer in the detection of biomolecules. Then a colorimetric protocol based on aptamer and conformational effects of water-soluble polythio-phene is reported. It is demonstrated that the protein sensor we designed is highly selective and sensitive, and the lowest detection limit with naked eyes is 63 nM.

KW - Aptamer

KW - Biosensors

KW - Conjugated polymer

KW - Protein

KW - Thrombin

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M3 - 文章

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JO - Nanjing Youdian Daxue Xuebao (Ziran Kexue Ban)/Journal of Nanjing University of Posts and Telecommunications (Natural Science)

JF - Nanjing Youdian Daxue Xuebao (Ziran Kexue Ban)/Journal of Nanjing University of Posts and Telecommunications (Natural Science)

IS - 1

ER -

Detection of thrombin based on the conformational effects of water-soluble conjugated polymer

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