Abstract
We introduce the application of water-soluble conjugated polymers and aptamer in the detection of biomolecules. Then a colorimetric protocol based on aptamer and conformational effects of water-soluble polythio-phene is reported. It is demonstrated that the protein sensor we designed is highly selective and sensitive, and the lowest detection limit with naked eyes is 63 nM.
| Original language | English |
|---|---|
| Pages (from-to) | 59-63 |
| Number of pages | 5 |
| Journal | Nanjing Youdian Daxue Xuebao (Ziran Kexue Ban)/Journal of Nanjing University of Posts and Telecommunications (Natural Science) |
| Volume | 28 |
| Issue number | 1 |
| State | Published - Feb 2008 |
| Externally published | Yes |
Keywords
- Aptamer
- Biosensors
- Conjugated polymer
- Protein
- Thrombin