TY - JOUR
T1 - Unique cytological behavior of MC3T3-E1 osteoblasts on H2O2-modified C/C composites in vitro
AU - Cao, Sheng
AU - Li, Hejun
AU - Lu, Jinhua
AU - Zhang, Leilei
N1 - Publisher Copyright:
© 2017, Science China Press and Springer-Verlag Berlin Heidelberg.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - MC3T3-E1 osteoblasts were cultured on H2O2-modified and unmodified carbon/carbon (H-C/C and C/C) composites for one week in order to evaluate differences in cell adhesion, spreading, and proliferation. The results indicated a certain degree of enhancement in the cell adhesion capability of osteoblasts cultured on H-C/C samples. Cellular morphologies after cell adhesion were observed via scanning electron microscopy (SEM), which showed that the cells adhered more closely and spread more widely on the H-C/C sample surface. However, no cell appeared in several multiple and continuous types of minor pores on both the C/C and H-C/C surfaces. In addition, two unique situations were observed on the H-C/C samples: an outline change of the osteoblasts was observed when the cells spread across some minor pores, and the cells entered and adhered well in some larger pores.
AB - MC3T3-E1 osteoblasts were cultured on H2O2-modified and unmodified carbon/carbon (H-C/C and C/C) composites for one week in order to evaluate differences in cell adhesion, spreading, and proliferation. The results indicated a certain degree of enhancement in the cell adhesion capability of osteoblasts cultured on H-C/C samples. Cellular morphologies after cell adhesion were observed via scanning electron microscopy (SEM), which showed that the cells adhered more closely and spread more widely on the H-C/C sample surface. However, no cell appeared in several multiple and continuous types of minor pores on both the C/C and H-C/C surfaces. In addition, two unique situations were observed on the H-C/C samples: an outline change of the osteoblasts was observed when the cells spread across some minor pores, and the cells entered and adhered well in some larger pores.
KW - carbon/carbon composites
KW - HO modification
KW - MC3T3-E1 osteoblasts
KW - surface wettability
UR - http://www.scopus.com/inward/record.url?scp=85035110014&partnerID=8YFLogxK
U2 - 10.1007/s40843-016-9015-9
DO - 10.1007/s40843-016-9015-9
M3 - 文章
AN - SCOPUS:85035110014
SN - 2095-8226
VL - 60
SP - 361
EP - 367
JO - Science China Materials
JF - Science China Materials
IS - 4
ER -