TY - GEN
T1 - Low-Melting Alloy Microfluidic Electrode Based on Hydrophobic Valve and its Application in Coulter Counter
AU - Yang, Dong
AU - Xun, Wenpeng
AU - Feng, Huicheng
AU - Chang, Honglong
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/6
Y1 - 2019/6
N2 - This paper presents a new method to fabricate low-melting point alloy (LMPA) electrodes inside polydimethylsiloxane (PDMS) microfluidic channels. The melting alloy is injected into a subchannel designed as a hydrophobic valve, which provides a threshold pressure to flow through. Thus, with an appropriate control of the injecting pressure, the melting alloy can fully fill the subchannel without passing through it and blocking the main channel. After the solidification, an LMPA microelectrode is formed and automatically aligned on the side of main channel. A Coulter counter microfluidic chip is fabricated using this method and a coefficient variation (CV) of 1.99% is obtained for 10-μm beads. The results show that the proposed method is a feasible solution to fabricate robust microelectrodes in polymer-based microfluidic chips without the expensive lithography or sputtering.
AB - This paper presents a new method to fabricate low-melting point alloy (LMPA) electrodes inside polydimethylsiloxane (PDMS) microfluidic channels. The melting alloy is injected into a subchannel designed as a hydrophobic valve, which provides a threshold pressure to flow through. Thus, with an appropriate control of the injecting pressure, the melting alloy can fully fill the subchannel without passing through it and blocking the main channel. After the solidification, an LMPA microelectrode is formed and automatically aligned on the side of main channel. A Coulter counter microfluidic chip is fabricated using this method and a coefficient variation (CV) of 1.99% is obtained for 10-μm beads. The results show that the proposed method is a feasible solution to fabricate robust microelectrodes in polymer-based microfluidic chips without the expensive lithography or sputtering.
KW - Coulter counter
KW - hydrophobic valve
KW - low-melting point alloy
KW - Microfluidic electrode
UR - http://www.scopus.com/inward/record.url?scp=85071901366&partnerID=8YFLogxK
U2 - 10.1109/TRANSDUCERS.2019.8808248
DO - 10.1109/TRANSDUCERS.2019.8808248
M3 - 会议稿件
AN - SCOPUS:85071901366
T3 - 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
SP - 1029
EP - 1032
BT - 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
Y2 - 23 June 2019 through 27 June 2019
ER -