High resolution optical coherence tomography for bio-imaging

Optical coherence tomography (OCT) is a low-coherence interferometry based bio-imaging technology. It has attracted extensive research interests in recent years for its non-invasive, high-speed and high-resolution properties. Numerous schemes for improving OCT resolutions have been demonstrated in literature. This chapter gives a comprehensive review of the recent developments of spectral domain (SD)-OCT systems with either high axial-resolution or lateral resolution, and then highlights the wide applications of such high-resolution OCT systems in biomedical imaging process. The influences of high-resolution OCT systems towards translational medicine are also discussed.