Exploring functional brain dynamics via a Bayesian connectivity change point model

Zhichao Lian, Xiang Li, Jianchuan Xing, Jinglei Lv, Xi Jiang, Dajiang Zhu, Shu Zhang, Jiansong Xu, Marc N. Potenza, Tianming Liu, Jing Zhang

科研成果: 书/报告/会议事项章节会议稿件同行评审

13 引用 (Scopus)

摘要

Multiple recent neuroimaging studies have demonstrated that the human brain's function undergoes remarkable temporal dynamics. However, quantitative characterization and modeling of such functional dynamics have been rarely explored. To fill this gap, we presents a novel Bayesian connectivity change point model (BCCPM), to analyze the joint probabilities among the nodes of brain networks between different time periods and statistically determine the boundaries of temporal blocks to estimate the change points. Intuitively, the determined change points represent the transitions of functional interaction patterns within the brain networks and can be used to investigate temporal functional brain dynamics. The BCCPM has been evaluated and validated by synthesized data. Also, the BCCPM has been applied to a real block-design task-based fMRI dataset and interesting results were obtained.

源语言英语
主期刊名2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
出版商Institute of Electrical and Electronics Engineers Inc.
600-603
页数4
ISBN(电子版)9781467319591
DOI
出版状态已出版 - 29 7月 2014
已对外发布
活动2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014 - Beijing, 中国
期限: 29 4月 20142 5月 2014

出版系列

姓名2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014

会议

会议2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014
国家/地区中国
Beijing
时期29/04/142/05/14

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