Development of two-channel phosphorescent core-shell nanoprobe for ratiometric and time-resolved luminescence imaging of intracellular oxygen levels

Huibin Sun, Jie Zhang, Kenneth Yin Zhang, Shujuan Liu, Hua Liang, Wen Lv, Weili Qiao, Xiangmei Liu, Tianshe Yang, Qiang Zhao, Wei Huang

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13 引用 (Scopus)

摘要

An effective strategy is developed to realize a ratiometric oxygen nanoprobe with two-channel phosphorescence signals based on a core-shell silica nanoparticle. This nanoprobe exhibits good water dispersibility and biocompatibility. Bioimaging experiments demonstrate that the nanoprobe can be used for monitoring the change in intracellular O2 concentration and performing quantitative O2 measurement through ratiometric and time- resolved luminescence bioimaging.

源语言英语
页(从-至)48-53
页数6
期刊Particle and Particle Systems Characterization
32
1
DOI
出版状态已出版 - 1 1月 2015
已对外发布

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