Accelerated cellular on- and off-target screening of bioactive compounds using microarrays

Jiaqi Fu, Zhenkun Na, Bo Peng, Mahesh Uttamchandani, Shao Q. Yao

科研成果: 期刊稿件文章同行评审

4 引用 (Scopus)

摘要

In situ proteome labeling was carried out with 9 drug-like probes in live mammalian cells, with the corresponding cellular targets captured on microarrays and simultaneously screened using a diverse set of antibodies, revealing potential on- and off-targets.

源语言英语
页(从-至)59-64
页数6
期刊Organic and Biomolecular Chemistry
14
1
DOI
出版状态已出版 - 2015
已对外发布

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