A novel improved procedure for the synthesis of oxazoles

Wei Huang, Jian Pei, Bingzi Chen, Weiwei Pei, Xiulin Ye

科研成果: 期刊稿件文章同行评审

52 引用 (Scopus)

摘要

In the present work a novel improved and convenient procedure for the synthesis of oxazoles has been developed. Acetamide, instead of ammonium acetate, was used to react with phenacyl benzoates in boiling xylene in the presence of BF3/Et2O as the catalyst. According to this new synthetic route, nine oxazole compounds were readily prepared as single products in reasonably high yields. On the basis of the experimental results, a plausible mechanism of this reaction is proposed.

源语言英语
页(从-至)10131-10136
页数6
期刊Tetrahedron
52
30
DOI
出版状态已出版 - 22 7月 1996
已对外发布

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