Quantitative study of droplet generation by pressure-driven microfluidic flows in a flow-focusing microdroplet generator

Wen Zeng, Bohang Wang, Honglong Chang, Pavel Neužil

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

To precisely control the size of droplets is of great importance for the applications of the droplet microfluidics. In a flow-focusing microdroplet generator, the pressure-driven microfluidic device is designed to control the flow rates of the fluids. For a specific geometry of the flow-focusing microchannel, a mathematical model of droplet formation is established, and the nonlinear relation between the droplet length and the driven-pressure ratio can be described by our model. For pressure-driven microfluidic flows, the nonlinear relation between the droplet length and the driving-pressure ratio is measured experimentally in the flow-focusing microchannel. Particularly, by using the closed-loop control method of droplet generation, good agreements are shown between the measured size of droplets and the predicted size of the droplets. As a result, the control precision of the droplet size can be increased drastically by the closed-loop control method of droplet generation. Consequently, monodisperse droplets of extremely small size can be produced in the flow-focusing microdroplet generator.

Original languageEnglish
Article number032009
JournalPhysics of Fluids
Volume36
Issue number3
DOIs
StatePublished - 1 Mar 2024

Fingerprint

Dive into the research topics of 'Quantitative study of droplet generation by pressure-driven microfluidic flows in a flow-focusing microdroplet generator'. Together they form a unique fingerprint.

Cite this