‘Old Drugs for New Applications’: Can Orthopedic Research Benefit from This Strategy?

Xiaohua Pan; Wenxiang Cheng; Jiali Wang; Ling Qin; Yuxiao Lai; Jian Tang; Peng Shang; Peigen Ren; Peng Zhang

doi:10.1177/1759720X11408487

‘Old Drugs for New Applications’: Can Orthopedic Research Benefit from This Strategy?

Xiaohua Pan, Wenxiang Cheng, Jiali Wang, Ling Qin, Yuxiao Lai, Jian Tang, Peng Shang, Peigen Ren, Peng Zhang

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

New drug exploration is difficult in a clinical setting and the development of new drugs may be costly and time consuming. With further research into the pathological mechanisms and etiology of diseases as well as the rapid development of biological techniques, many ‘old drugs’ that have been applied in clinics may have new therapeutic functions which may shed light on clinical management. Based on this, we have investigated the ‘old drugs for new applications’ strategy in pharmacology which may be less expensive and more efficient in the clinical setting. In this paper we have explored and illustrated the potential applications of ‘old drugs’ for the treatment of orthopedic diseases, especially in arthritis and osteoporosis therapy.

Original language	English
Pages (from-to)	201-205
Number of pages	5
Journal	Therapeutic Advances in Musculoskeletal Disease
Volume	3
Issue number	4
DOIs	https://doi.org/10.1177/1759720X11408487
State	Published - Aug 2011
Externally published	Yes

Keywords

cholinergic anti-inflammatory pathway
cholinergic antinociceptive pathway
old drugs for new applications
orthopedic research
rheumatoid arthritis

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10.1177/1759720X11408487

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title = "{\textquoteleft}Old Drugs for New Applications{\textquoteright}: Can Orthopedic Research Benefit from This Strategy?",

abstract = "New drug exploration is difficult in a clinical setting and the development of new drugs may be costly and time consuming. With further research into the pathological mechanisms and etiology of diseases as well as the rapid development of biological techniques, many {\textquoteleft}old drugs{\textquoteright} that have been applied in clinics may have new therapeutic functions which may shed light on clinical management. Based on this, we have investigated the {\textquoteleft}old drugs for new applications{\textquoteright} strategy in pharmacology which may be less expensive and more efficient in the clinical setting. In this paper we have explored and illustrated the potential applications of {\textquoteleft}old drugs{\textquoteright} for the treatment of orthopedic diseases, especially in arthritis and osteoporosis therapy.",

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author = "Xiaohua Pan and Wenxiang Cheng and Jiali Wang and Ling Qin and Yuxiao Lai and Jian Tang and Peng Shang and Peigen Ren and Peng Zhang",

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AU - Pan, Xiaohua

AU - Cheng, Wenxiang

AU - Wang, Jiali

AU - Qin, Ling

AU - Lai, Yuxiao

AU - Tang, Jian

AU - Shang, Peng

AU - Ren, Peigen

AU - Zhang, Peng

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AB - New drug exploration is difficult in a clinical setting and the development of new drugs may be costly and time consuming. With further research into the pathological mechanisms and etiology of diseases as well as the rapid development of biological techniques, many ‘old drugs’ that have been applied in clinics may have new therapeutic functions which may shed light on clinical management. Based on this, we have investigated the ‘old drugs for new applications’ strategy in pharmacology which may be less expensive and more efficient in the clinical setting. In this paper we have explored and illustrated the potential applications of ‘old drugs’ for the treatment of orthopedic diseases, especially in arthritis and osteoporosis therapy.

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M3 - 文献综述

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‘Old Drugs for New Applications’: Can Orthopedic Research Benefit from This Strategy?

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Keywords

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