Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device

Adrian J.T. Teo; King Ho Holden Li; Nam Trung Nguyen; Wei Guo; Nadine Heere; Heng Dong Xi; Chia Wen Tsao; Weihua Li; Say Hwa Tan

doi:10.1021/acs.analchem.6b05053

Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device

Adrian J.T. Teo, King Ho Holden Li, Nam Trung Nguyen, Wei Guo, Nadine Heere, Heng Dong Xi, Chia Wen Tsao, Weihua Li, Say Hwa Tan

School of Aeronautics

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.

Original language	English
Pages (from-to)	4387-4391
Number of pages	5
Journal	Analytical Chemistry
Volume	89
Issue number	8
DOIs	https://doi.org/10.1021/acs.analchem.6b05053
State	Published - 18 Apr 2017

Access to Document

10.1021/acs.analchem.6b05053

Cite this

@article{5331446031274be69347b5efbcccfcf0,

title = "Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device",

abstract = "We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.",

author = "Teo, {Adrian J.T.} and Li, {King Ho Holden} and Nguyen, {Nam Trung} and Wei Guo and Nadine Heere and Xi, {Heng Dong} and Tsao, {Chia Wen} and Weihua Li and Tan, {Say Hwa}",

note = "Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",

year = "2017",

month = apr,

day = "18",

doi = "10.1021/acs.analchem.6b05053",

language = "英语",

volume = "89",

pages = "4387--4391",

journal = "Analytical Chemistry",

issn = "0003-2700",

publisher = "American Chemical Society",

number = "8",

}

TY - JOUR

T1 - Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device

AU - Teo, Adrian J.T.

AU - Li, King Ho Holden

AU - Nguyen, Nam Trung

AU - Guo, Wei

AU - Heere, Nadine

AU - Xi, Heng Dong

AU - Tsao, Chia Wen

AU - Li, Weihua

AU - Tan, Say Hwa

PY - 2017/4/18

Y1 - 2017/4/18

N2 - We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.

AB - We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.

UR - http://www.scopus.com/inward/record.url?scp=85019985542&partnerID=8YFLogxK

U2 - 10.1021/acs.analchem.6b05053

DO - 10.1021/acs.analchem.6b05053

M3 - 文章

C2 - 28192966

AN - SCOPUS:85019985542

SN - 0003-2700

VL - 89

SP - 4387

EP - 4391

JO - Analytical Chemistry

JF - Analytical Chemistry

IS - 8

ER -

Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device

Abstract

Access to Document

Other files and links

Fingerprint

Cite this