TY - GEN
T1 - Joint analysis of fiber shape and cortical folding patterns
AU - Hu, Xintao
AU - Guo, Lei
AU - Zhang, Tuo
AU - Li, Gang
AU - Nie, Jingxin
AU - Jiang, Xi
AU - Zhang, Degang
AU - Liu, Tianming
PY - 2010
Y1 - 2010
N2 - Quantitative descriptions of white matter (WM) fiber shape and cortical folding patterns are important for neuroscience research. This paper presents a novel computational method for WM fiber shape pattern analysis, that is, WM fibers are clustered into five primitive shape patterns: closed 'U', 'M', curved line, open 'U' and straight line, based on the automatic clustering of their shape features. We study the correlation between the fiber shape patterns and the folding patterns of cortical regions that the fibers connect, and find that these patterns are highly correlated. Also, we investigate the shape patterns of the WM fibers that connect different brain regions such as cortical lobes and subcortical regions, and find that the shape patterns of the fibers connecting different brain regions are quite specific. These results might provide insights into the structural and functional architecture of the human brain.
AB - Quantitative descriptions of white matter (WM) fiber shape and cortical folding patterns are important for neuroscience research. This paper presents a novel computational method for WM fiber shape pattern analysis, that is, WM fibers are clustered into five primitive shape patterns: closed 'U', 'M', curved line, open 'U' and straight line, based on the automatic clustering of their shape features. We study the correlation between the fiber shape patterns and the folding patterns of cortical regions that the fibers connect, and find that these patterns are highly correlated. Also, we investigate the shape patterns of the WM fibers that connect different brain regions such as cortical lobes and subcortical regions, and find that the shape patterns of the fibers connecting different brain regions are quite specific. These results might provide insights into the structural and functional architecture of the human brain.
KW - Correlation matrix map
KW - Cortical folding patterns
KW - Fiber shape
UR - http://www.scopus.com/inward/record.url?scp=77955207093&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2010.5490201
DO - 10.1109/ISBI.2010.5490201
M3 - 会议稿件
AN - SCOPUS:77955207093
SN - 9781424441266
T3 - 2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings
SP - 1165
EP - 1168
BT - 2010 7th IEEE International Symposium on Biomedical Imaging
T2 - 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
Y2 - 14 April 2010 through 17 April 2010
ER -