In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang; Linxiao Yang; Haixia Wang; Gerd Ulrich Nienhaus

doi:10.1002/smll.201503316

In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

Li Shang, Linxiao Yang, Haixia Wang, Gerd Ulrich Nienhaus

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.

Original language	English
Pages (from-to)	868-873
Number of pages	6
Journal	Small
Volume	12
Issue number	7
DOIs	https://doi.org/10.1002/smll.201503316
State	Published - 17 Feb 2016
Externally published	Yes

Keywords

fluorescence lifetime imaging microscopy
live cells
luminescent probes
nanoparticles
quantum dots

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10.1002/smll.201503316

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abstract = "FLIMaging nanoparticle degradation: semiconductor and metal nanoparticle degradation has been observed in live cells over 3 d via the change of the characteristic luminescence lifetime using fluorescence lifetime imaging microscopy (FLIM). Thus, FLIM is a simple yet robust tool to examine the intracellular stability of photoluminescent nanoparticles in live cells, tissues, and organisms.",

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author = "Li Shang and Linxiao Yang and Haixia Wang and Nienhaus, {Gerd Ulrich}",

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AU - Wang, Haixia

AU - Nienhaus, Gerd Ulrich

PY - 2016/2/17

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KW - fluorescence lifetime imaging microscopy

KW - live cells

KW - luminescent probes

KW - nanoparticles

KW - quantum dots

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In Situ Monitoring of the Intracellular Stability of Nanoparticles by Using Fluorescence Lifetime Imaging

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Keywords

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