FDCluster: Mining frequent closed discriminative bicluster without candidate maintenance in multiple microarray datasets

Miao Wang, Xuequn Shang, Shaohua Zhang, Zhanhuai Li

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

18 Scopus citations

Abstract

Biclustering is a methodology allowing for condition set and gene set points clustering simultaneously. Almost all the current biclustering algorithms find bicluster in one microarray dataset. In order to reduce the noise influence and find more biological biclusters, we propose an algorithm, FDCluster, to mine frequent closed discriminative bicluster in multiple microarray datasets. FDCluster uses Apriori property and several novel techniques for pruning to mine frequent closed bicluster without candidate maintenance. The experimental results show that FDCluster is more effectiveness than traditional method in either single micorarray dataset or multiple microarray datasets. We also test the biological significance using GO to show our proposed method is able to produce biologically relevant biclusters.

Original languageEnglish
Title of host publicationProceedings - 10th IEEE International Conference on Data Mining Workshops, ICDMW 2010
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages779-786
Number of pages8
ISBN (Print)9780769542577
DOIs
StatePublished - 2010

Publication series

NameProceedings - IEEE International Conference on Data Mining, ICDM
ISSN (Print)1550-4786

Keywords

  • Biclustering
  • Frequent closed discriminative bicluster
  • Microarray
  • Weighted undirected sample relational graph

Fingerprint

Dive into the research topics of 'FDCluster: Mining frequent closed discriminative bicluster without candidate maintenance in multiple microarray datasets'. Together they form a unique fingerprint.

Cite this