Extinction effects of multiplicative non-gaussian lévy noise in a tumor growth system with immunization

Meng Li Hao, Wei Xu, Dong Xi Li, Di Liu

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The extinction phenomenon induced by multiplicative non-Gaussian Lévy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in terms of a stochastic differential equation with multiplicative noise. By means of the theory of the infinitesimal generator of Hunt processes, the escape probability, which is used to measure the noise-induced extinction probability of tumor cells, is explicitly expressed as a function of initial tumor cell density, stability index and noise intensity. Based on the numerical calculations, it is found that for different initial densities of tumor cells, noise parameters play opposite roles on the escape probability. The optimally selected values of the multiplicative noise intensity and the stability index are found to maximize the escape probability.

Original languageEnglish
Pages (from-to)571-577
Number of pages7
JournalCommunications in Theoretical Physics
Volume61
Issue number5
DOIs
StatePublished - May 2014

Keywords

  • model of tumor growth
  • noise-induced extinction probability
  • non-Gaussian Lévy motion
  • stochastic immune rate

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