Embracing Disease Progression with a Learning System for Real World Evidence Discovery

Zefang Tang, Lun Hu, Xu Min, Yuan Zhang, Jing Mei, Kenney Ng, Shaochun Li, Pengwei Hu, Zhuhong You

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Electronic Health Records (EHRs) have been widely used in healthcare studies recently, such as the analyses for patient diagnostic outcome and understanding of disease progression. EHR is a treasure for researchers who conduct the Real-World study to discovering Real-World Evidence (RWE). In this paper, we design an end-to-end learning system for disease states discovery based on a data-driven strategy. A large-scale proprietary EHR data mart containing about 55 million patients with over 20 billion data records is used for data extraction and analysis. Given a disease of interest, researchers could easily obtain the hidden disease states. Once our system were operational, biomedical researchers could get the results for downstream analyses such as disease prediction, drug design and outcome analyses.

Original languageEnglish
Title of host publicationIntelligent Computing Theories and Application - 16th International Conference, ICIC 2020, Proceedings
EditorsDe-Shuang Huang, Kang-Hyun Jo
PublisherSpringer Science and Business Media Deutschland GmbH
Pages524-534
Number of pages11
ISBN (Print)9783030608019
DOIs
StatePublished - 2020
Externally publishedYes
Event16th International Conference on Intelligent Computing, ICIC 2020 - Bari , Italy
Duration: 2 Oct 20205 Oct 2020

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12464 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference16th International Conference on Intelligent Computing, ICIC 2020
Country/TerritoryItaly
CityBari
Period2/10/205/10/20

Keywords

  • Biomedical analyses
  • Disease progression
  • EHRs
  • Real World Evidence discovery

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