Effect of protein adsorption on the fluorescence of ultrasmall gold nanoclusters

Li Shang; Stefan Brandholt; Florian Stockmar; Vanessa Trouillet; Michael Bruns; G. Ulrich Nienhaus

doi:10.1002/smll.201101353

Effect of protein adsorption on the fluorescence of ultrasmall gold nanoclusters

Li Shang, Stefan Brandholt, Florian Stockmar, Vanessa Trouillet, Michael Bruns, G. Ulrich Nienhaus

Research output: Contribution to journal › Article › peer-review

166 Scopus citations

Abstract

The interaction of proteins with ultrasmall gold nanoclusters (Au NCs) is investigated. Upon protein association, the fluorescence of Au NCs is significantly enhanced and, concomitantly, their luminescence lifetime is prolonged. The results stress the importance of investigating the behavior of fluorescent metal NCs in complex biological environment for advancing their bio-nanotechnology applications.

Original language	English
Pages (from-to)	661-665
Number of pages	5
Journal	Small
Volume	8
Issue number	5
DOIs	https://doi.org/10.1002/smll.201101353
State	Published - 12 Mar 2012
Externally published	Yes

Keywords

fluorescence enhancement
gold nanoclusters
protein adsorption
protein-nanoparticle interactions

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10.1002/smll.201101353

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abstract = "The interaction of proteins with ultrasmall gold nanoclusters (Au NCs) is investigated. Upon protein association, the fluorescence of Au NCs is significantly enhanced and, concomitantly, their luminescence lifetime is prolonged. The results stress the importance of investigating the behavior of fluorescent metal NCs in complex biological environment for advancing their bio-nanotechnology applications.",

keywords = "fluorescence enhancement, gold nanoclusters, protein adsorption, protein-nanoparticle interactions",

author = "Li Shang and Stefan Brandholt and Florian Stockmar and Vanessa Trouillet and Michael Bruns and Nienhaus, {G. Ulrich}",

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AU - Brandholt, Stefan

AU - Stockmar, Florian

AU - Trouillet, Vanessa

AU - Bruns, Michael

AU - Nienhaus, G. Ulrich

PY - 2012/3/12

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AB - The interaction of proteins with ultrasmall gold nanoclusters (Au NCs) is investigated. Upon protein association, the fluorescence of Au NCs is significantly enhanced and, concomitantly, their luminescence lifetime is prolonged. The results stress the importance of investigating the behavior of fluorescent metal NCs in complex biological environment for advancing their bio-nanotechnology applications.

KW - fluorescence enhancement

KW - gold nanoclusters

KW - protein adsorption

KW - protein-nanoparticle interactions

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Effect of protein adsorption on the fluorescence of ultrasmall gold nanoclusters

Abstract

Keywords

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