Dual spectrometer system with spectral compounding for 1-μm optical coherence tomography in vivo

Dongyao Cui, Xinyu Liu, Jing Zhang, Xiaojun Yu, Sun Ding, Yuemei Luo, Jun Gu, Ping Shum, Linbo Liu

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

1 μm axial resolution spectral domain optical coherence tomography (OCT) is demonstrated for in vivo cellular resolution imaging. Output of two superluminescent diode sources is combined to provide near infrared illumination from 755 to 1105 nm. The spectral interference is detected using two spectrometers basedon a Si camera and an InGaAs camera, respectively. Spectra from the two spectrometers are combined to achieve an axial resolution of 1.27 μm in air. Imaging was conducted on zebra fish larvae to visualize cellular details.

Original languageEnglish
Pages (from-to)6727-6730
Number of pages4
JournalOptics Letters
Volume39
Issue number23
DOIs
StatePublished - 1 Dec 2014
Externally publishedYes

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