Cyclodextrin-based hyperbranched polymers: Molecule design, synthesis, and characterization

Wei Tian, Xiaodong Fan, Jie Kong, Tao Liu, Yuyang Liu, Yi Huang, Shengjie Wang, Guobin Zhang

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

The cyclodextrin (CD) molecule, a host for a variety of smaller molecular guests, and hyperbranched polymers both possess molecule cavities in their molecular architectures. If the hyperbranched poly(β-cyclodextrin)s are established using modified β-CD molecules as monomers, their molecular inclusion capabilities for smaller molecular guests may be enhanced due to the combination of two different molecule cavities from both their hyperbranched topography architecture and CD molecule chain segments. Herein, three types of hyperbranched poly (β-cyclodextrin)s, i.e., HBP-ABx from AB x-type β-CD monomers, HBP-(By + ABx) from By core molecules and ABx-type β-CD monomers, and water-soluble HBP-AB2 from AB2-type β-CD monomers, were synthesized via hydrosilylation reaction under the thermal or ultraviolet activated polymerization. The hyperbranched structures of resultant poly(β-cyclodextrin)s were characterized using 1H NMR, 13C NMR, 29Si NMR, 1H-29Si heteronuclear multiple bond correlation, and size exclusion chromatography/ multiangle laser light scattering (SEC/MALLS). The molecule inclusion and recognition behaviors of the novel hyperbranched poly β-cyclodextrin)s as well as their macromolecular structures, degree of branching, and thermal properties were investigated in detail. UV - vis spectroscopy results show that HBP-AB2 has molecular inclusion capabilities and also can form inclusion complexation with single or double guests, including phenolphthalein (PP) and methyl orange (MO). Compared with AB2-type β-CD monomer, the molecular inclusion capability of the hyperbranched polymer was enhanced. Furthermore, HBP-AB2 presents molecular recognition behavior when MO solution is added into their PP solution.

Original languageEnglish
Pages (from-to)640-651
Number of pages12
JournalMacromolecules
Volume42
Issue number3
DOIs
StatePublished - 10 Feb 2009

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