Assessment of micro-optical coherence tomography (μOCT) as an imaging tool for pancreatic disease diagnosis

Chi Hu, Xiaojun Yu, Qianshan Ding, Ganggang Mu, Yunchao Deng, Honggang Yu, Linbo Liu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

As an emerging technique capable of providing cellular/subcellular-level tissue microstructure images, optical coherence tomography (OCT) is regarded to be a viable tool for early disease diagnosis, yet few studies on pancreatic imaging have ever been reported in literature. In this paper, we utilized a lab-built micro-OCT (μOCT) for cellular/subcellular pancreatic imaging for both normal tissues and those specimens with edema, and evaluate the feasibility of OCT as an imaging tool for early pancreatic disease diagnosis. Results show that the cellular/subcellular-level pancreatic microstructures of normal tissues could be clearly identified, and is quite different from those in tissues with edema. Such results demonstrate the great potential of μOCT as a viable tool for pancreatic tissue imaging in clinical practice.

Original languageEnglish
Title of host publicationBiomedical Imaging and Sensing Conference
EditorsToyohiko Yatagai, Yoshihisa Aizu, Osamu Matoba, Yasuhiro Awatsuji, Yuan Luo
PublisherSPIE
ISBN (Electronic)9781510619791
DOIs
StatePublished - 2018
EventBiomedical Imaging and Sensing Conference 2018 - Yokohama, Japan
Duration: 25 Apr 201827 Apr 2018

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10711
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceBiomedical Imaging and Sensing Conference 2018
Country/TerritoryJapan
CityYokohama
Period25/04/1827/04/18

Keywords

  • disease diagnosis
  • high-resolution
  • Optical coherence tomography
  • pancreatic imaging
  • tissue morphology

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