A Versatile Hydrophilic and Antifouling Coating Based on Dopamine Modified Four-Arm Polyethylene Glycol by One-Step Synthesis Method

Xue Ting Wang; Xudong Deng; Tuo Di Zhang; Jie Zhang; Liang Liang Chen; Yi Fan Wang; Xin Cao; Yao Zhong Zhang; Xing Zheng; Da Chuan Yin

doi:10.1021/acsmacrolett.2c00277

A Versatile Hydrophilic and Antifouling Coating Based on Dopamine Modified Four-Arm Polyethylene Glycol by One-Step Synthesis Method

Xue Ting Wang, Xudong Deng, Tuo Di Zhang, Jie Zhang, Liang Liang Chen, Yi Fan Wang, Xin Cao, Yao Zhong Zhang, Xing Zheng, Da Chuan Yin

School of life sciences

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

A versatile hydrophilic and antifouling coating was designed and prepared based on catechol-modified four-arm polyethylene glycol. The dopamine (DA) molecules were grafted onto the end of the four-arm polyethylene glycol carboxyl (4A-PEG-COOH) through the amidation reaction, which was proven by 1H NMR and FTIR analysis, assisting the strong adhesion of PEG on the surface of various types of materials, including metallic, inorganic, and polymeric materials. The reduction of the water contact angle and the bacteria-repellent and protein-repellent effects indicated that the coating had good hydrophilicity and antifouling performance. Raman spectroscopy analysis demonstrated the affinity between the polymeric surface and water, which further confirmed the hydrophilicity of the coating. Finally, in vitro cytotoxicity assay demonstrated good biocompatibility of the coating layer.

Original language	English
Pages (from-to)	805-812
Number of pages	8
Journal	ACS Macro Letters
Volume	11
DOIs	https://doi.org/10.1021/acsmacrolett.2c00277
State	Published - 2022

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10.1021/acsmacrolett.2c00277

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title = "A Versatile Hydrophilic and Antifouling Coating Based on Dopamine Modified Four-Arm Polyethylene Glycol by One-Step Synthesis Method",

abstract = "A versatile hydrophilic and antifouling coating was designed and prepared based on catechol-modified four-arm polyethylene glycol. The dopamine (DA) molecules were grafted onto the end of the four-arm polyethylene glycol carboxyl (4A-PEG-COOH) through the amidation reaction, which was proven by 1H NMR and FTIR analysis, assisting the strong adhesion of PEG on the surface of various types of materials, including metallic, inorganic, and polymeric materials. The reduction of the water contact angle and the bacteria-repellent and protein-repellent effects indicated that the coating had good hydrophilicity and antifouling performance. Raman spectroscopy analysis demonstrated the affinity between the polymeric surface and water, which further confirmed the hydrophilicity of the coating. Finally, in vitro cytotoxicity assay demonstrated good biocompatibility of the coating layer.",

author = "Wang, {Xue Ting} and Xudong Deng and Zhang, {Tuo Di} and Jie Zhang and Chen, {Liang Liang} and Wang, {Yi Fan} and Xin Cao and Zhang, {Yao Zhong} and Xing Zheng and Yin, {Da Chuan}",

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year = "2022",

doi = "10.1021/acsmacrolett.2c00277",

language = "英语",

volume = "11",

pages = "805--812",

journal = "ACS Macro Letters",

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TY - JOUR

T1 - A Versatile Hydrophilic and Antifouling Coating Based on Dopamine Modified Four-Arm Polyethylene Glycol by One-Step Synthesis Method

AU - Wang, Xue Ting

AU - Deng, Xudong

AU - Zhang, Tuo Di

AU - Zhang, Jie

AU - Chen, Liang Liang

AU - Wang, Yi Fan

AU - Cao, Xin

AU - Zhang, Yao Zhong

AU - Zheng, Xing

AU - Yin, Da Chuan

PY - 2022

Y1 - 2022

N2 - A versatile hydrophilic and antifouling coating was designed and prepared based on catechol-modified four-arm polyethylene glycol. The dopamine (DA) molecules were grafted onto the end of the four-arm polyethylene glycol carboxyl (4A-PEG-COOH) through the amidation reaction, which was proven by 1H NMR and FTIR analysis, assisting the strong adhesion of PEG on the surface of various types of materials, including metallic, inorganic, and polymeric materials. The reduction of the water contact angle and the bacteria-repellent and protein-repellent effects indicated that the coating had good hydrophilicity and antifouling performance. Raman spectroscopy analysis demonstrated the affinity between the polymeric surface and water, which further confirmed the hydrophilicity of the coating. Finally, in vitro cytotoxicity assay demonstrated good biocompatibility of the coating layer.

AB - A versatile hydrophilic and antifouling coating was designed and prepared based on catechol-modified four-arm polyethylene glycol. The dopamine (DA) molecules were grafted onto the end of the four-arm polyethylene glycol carboxyl (4A-PEG-COOH) through the amidation reaction, which was proven by 1H NMR and FTIR analysis, assisting the strong adhesion of PEG on the surface of various types of materials, including metallic, inorganic, and polymeric materials. The reduction of the water contact angle and the bacteria-repellent and protein-repellent effects indicated that the coating had good hydrophilicity and antifouling performance. Raman spectroscopy analysis demonstrated the affinity between the polymeric surface and water, which further confirmed the hydrophilicity of the coating. Finally, in vitro cytotoxicity assay demonstrated good biocompatibility of the coating layer.

UR - http://www.scopus.com/inward/record.url?scp=85132455916&partnerID=8YFLogxK

U2 - 10.1021/acsmacrolett.2c00277

DO - 10.1021/acsmacrolett.2c00277

M3 - 文章

C2 - 35666550

AN - SCOPUS:85132455916

SN - 2161-1653

VL - 11

SP - 805

EP - 812

JO - ACS Macro Letters

JF - ACS Macro Letters

ER -

A Versatile Hydrophilic and Antifouling Coating Based on Dopamine Modified Four-Arm Polyethylene Glycol by One-Step Synthesis Method

Abstract

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