A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

Xiang Li; Yufu Tang; Jie Li; Xiaoming Hu; Chao Yin; Zhen Yang; Qi Wang; Zizi Wu; Xiaomei Lu; Wenjun Wang; Wei Huang; Quli Fan

doi:10.1039/c9cc02224d

A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

Xiang Li, Yufu Tang, Jie Li, Xiaoming Hu, Chao Yin, Zhen Yang, Qi Wang, Zizi Wu, Xiaomei Lu, Wenjun Wang, Wei Huang, Quli Fan

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H₂S with chlorine. The probe demonstrated specific response to H₂S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H₂S in vivo.

Original language	English
Pages (from-to)	5934-5937
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	42
DOIs	https://doi.org/10.1039/c9cc02224d
State	Published - 2019
Externally published	Yes

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title = "A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice",

abstract = "A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H2S in vivo.",

author = "Xiang Li and Yufu Tang and Jie Li and Xiaoming Hu and Chao Yin and Zhen Yang and Qi Wang and Zizi Wu and Xiaomei Lu and Wenjun Wang and Wei Huang and Quli Fan",

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doi = "10.1039/c9cc02224d",

language = "英语",

volume = "55",

pages = "5934--5937",

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T1 - A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

AU - Li, Xiang

AU - Tang, Yufu

AU - Li, Jie

AU - Hu, Xiaoming

AU - Yin, Chao

AU - Yang, Zhen

AU - Wang, Qi

AU - Wu, Zizi

AU - Lu, Xiaomei

AU - Wang, Wenjun

AU - Huang, Wei

AU - Fan, Quli

PY - 2019

Y1 - 2019

N2 - A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H2S in vivo.

AB - A small-molecule photoacoustic probe based on cyanine dyes was developed by taking advantage of the nucleophilic substitution reaction of H2S with chlorine. The probe demonstrated specific response to H2S with ratiometric photoacoustic signals in the NIR region, which enabled real-time, accurate, high-resolution imaging of endogenous H2S in vivo.

UR - http://www.scopus.com/inward/record.url?scp=85066241120&partnerID=8YFLogxK

U2 - 10.1039/c9cc02224d

DO - 10.1039/c9cc02224d

M3 - 文章

C2 - 31049519

AN - SCOPUS:85066241120

SN - 1359-7345

VL - 55

SP - 5934

EP - 5937

JO - Chemical Communications

JF - Chemical Communications

IS - 42

ER -

A small-molecule probe for ratiometric photoacoustic imaging of hydrogen sulfide in living mice

Abstract

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