A Novel Single Cell Culture Chip Based on One-Step Method

Fang Ye; Meiying He; Jin Xie; Li Xie; Honglong Chang; Weizheng Yuan

doi:10.1051/jnwpu/20183610132

A Novel Single Cell Culture Chip Based on One-Step Method

Fang Ye, Meiying He, Jin Xie, Li Xie, Honglong Chang, Weizheng Yuan

Research output: Contribution to journal › Article › peer-review

Abstract

More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

Original language	English
Pages (from-to)	132-138
Number of pages	7
Journal	Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University
Volume	36
Issue number	1
DOIs	https://doi.org/10.1051/jnwpu/20183610132
State	Published - Feb 2018

Keywords

Micropattern
MIMIC
PolyHEMA
Single cell culture

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10.1051/jnwpu/20183610132

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abstract = "More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.",

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author = "Fang Ye and Meiying He and Jin Xie and Li Xie and Honglong Chang and Weizheng Yuan",

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AU - He, Meiying

AU - Xie, Jin

AU - Xie, Li

AU - Chang, Honglong

AU - Yuan, Weizheng

PY - 2018/2

Y1 - 2018/2

N2 - More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

AB - More and more basic biology research focus on the single cell level. However, the way to fabricate a chemically patterned surface exist some questions such as complex fabrication process, graphic quality puzzle and so on. In this paper, we present a One-Step method based on Poly 2-hydroxyethyl methacrylate (PolyHEMA) and micromolding in capillaries (MIMIC) technology to fabricate single cell culture chip. Experimental evidence indicates that the integrity and stability of the PolyHEMA pattern can perfectly satisfy the need of long-term cell culture.

KW - Micropattern

KW - MIMIC

KW - PolyHEMA

KW - Single cell culture

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JO - Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University

JF - Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University

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ER -

A Novel Single Cell Culture Chip Based on One-Step Method

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Keywords

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