A Guided Attention 4D Convolutional Neural Network for Modeling Spatio-Temporal Patterns of Functional Brain Networks

Jiadong Yan, Yu Zhao, Mingxin Jiang, Shu Zhang, Tuo Zhang, Shimin Yang, Yuzhong Chen, Zhongbo Zhao, Zhibin He, Benjamin Becker, Tianming Liu, Keith Kendrick, Xi Jiang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Since the complex brain functions are achieved by the interaction of functional brain networks with the specific spatial distributions and temporal dynamics, modeling the spatial and temporal patterns of functional brain networks based on 4D fMRI data offers a way to understand the brain functional mechanisms. Matrix decomposition methods and deep learning methods have been developed to provide solutions. However, the underlying nature of functional brain networks remains unclear due to underutilizing the spatio-temporal characteristics of 4D fMRI input in previous methods. To address this problem, we propose a novel Guided Attention 4D Convolutional Neural Network (GA-4DCNN) to model spatial and temporal patterns of functional brain networks simultaneously. GA-4DCNN consists of two subnetworks: the spatial 4DCNN and the temporal Guided Attention (GA) network. The 4DCNN firstly extracts spatio-temporal characteristics of fMRI input to model the spatial pattern, while the GA network further models the corresponding temporal pattern guided by the modeled spatial pattern. Based on two task fMRI datasets from the Human Connectome Project, experimental results show that the proposed GA-4DCNN has superior ability and generalizability in modeling spatial and temporal patterns compared to other state-of-the-art methods. This study provides a new useful tool for modeling and understanding brain function.

Original languageEnglish
Title of host publicationPattern Recognition and Computer Vision - 4th Chinese Conference, PRCV 2021, Proceedings
EditorsHuimin Ma, Liang Wang, Changshui Zhang, Fei Wu, Tieniu Tan, Yaonan Wang, Jianhuang Lai, Yao Zhao
PublisherSpringer Science and Business Media Deutschland GmbH
Pages350-361
Number of pages12
ISBN (Print)9783030880095
DOIs
StatePublished - 2021
Event4th Chinese Conference on Pattern Recognition and Computer Vision, PRCV 2021 - Beijing, China
Duration: 29 Oct 20211 Nov 2021

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume13021 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference4th Chinese Conference on Pattern Recognition and Computer Vision, PRCV 2021
Country/TerritoryChina
CityBeijing
Period29/10/211/11/21

Keywords

  • 4D convolutional neural network
  • Functional brain network
  • Functional MRI
  • Guided attention
  • Spatio-temporal pattern

Fingerprint

Dive into the research topics of 'A Guided Attention 4D Convolutional Neural Network for Modeling Spatio-Temporal Patterns of Functional Brain Networks'. Together they form a unique fingerprint.

Cite this