摘要
A transition metal-free aldol condensation/[1+2+3] annulation reaction of isocyanoacetates with 8-(alkynyl)-1-naphthaldehydes has been developed for the general synthesis of azafluoranthenes. This domino reaction enables successive formation of three new bonds and two rings from readily accessible starting materials in a single operation. Furthermore, this methodology can also be utilized to construct chromeno[4,3-c]pyridines and benzo[c][2,6]naphthyridines in moderate yields.
源语言 | 英语 |
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页(从-至) | 4855-4858 |
页数 | 4 |
期刊 | Chemical Communications |
卷 | 57 |
期 | 39 |
DOI | |
出版状态 | 已出版 - 14 5月 2021 |