TY - JOUR
T1 - Temporal variability of cortical gyral-sulcal resting state functional activity correlates with fluid intelligence
AU - Yang, Shimin
AU - Zhao, Zhongbo
AU - Cui, Han
AU - Zhang, Tuo
AU - Zhao, Lin
AU - He, Zhibin
AU - Liu, Huan
AU - Guo, Lei
AU - Liu, Tianming
AU - Becker, Benjamin
AU - Kendrick, Keith M.
AU - Jiang, Xi
N1 - Publisher Copyright:
© 2019 Yang, Zhao, Cui, Zhang, Zhao, He, Liu, Guo, Liu, Becker, Kendrick and Jiang.
PY - 2019/4/24
Y1 - 2019/4/24
N2 - The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been reported to date to elucidate the functional difference between gyri and sulci, the temporal variability of functional activity, which could explain individual differences in learning and higher-order cognitive functions, and as well as differences in gyri and sulci, remains to be explored. The present study explored the temporal variability of cortical gyral-sulcal resting state functional activity and its association with fluid intelligence measures on the Human Connectome Project dataset. We found that the temporal variance of resting state fMRI BOLD signal was significantly larger in gyri than in sulci. We also found that the temporal variability of certain regions including middle frontal cortex, inferior parietal lobe and visual cortex was positively associated with fluid intelligence. Moreover, those regions were predominately located in gyri rather than in sulci. This study reports initial evidence for temporal variability difference of functional activity between gyri and sulci, and its association with fluid intelligence measures, and thus provides novel insights to understand the mechanism and functional relevance of gyri and sulci.
AB - The human cerebral cortex is highly convoluted as convex gyri and concave sulci. In the past decades, extensive studies have consistently revealed substantial differences between gyri and sulci in terms of genetics, anatomy, morphology, axonal fiber connections, and function. Although interesting findings have been reported to date to elucidate the functional difference between gyri and sulci, the temporal variability of functional activity, which could explain individual differences in learning and higher-order cognitive functions, and as well as differences in gyri and sulci, remains to be explored. The present study explored the temporal variability of cortical gyral-sulcal resting state functional activity and its association with fluid intelligence measures on the Human Connectome Project dataset. We found that the temporal variance of resting state fMRI BOLD signal was significantly larger in gyri than in sulci. We also found that the temporal variability of certain regions including middle frontal cortex, inferior parietal lobe and visual cortex was positively associated with fluid intelligence. Moreover, those regions were predominately located in gyri rather than in sulci. This study reports initial evidence for temporal variability difference of functional activity between gyri and sulci, and its association with fluid intelligence measures, and thus provides novel insights to understand the mechanism and functional relevance of gyri and sulci.
KW - Cortical folding
KW - Fluid intelligence
KW - Functional activity
KW - Gyri and sulci
KW - Resting state fMRI
KW - Temporal variability
UR - http://www.scopus.com/inward/record.url?scp=85066983254&partnerID=8YFLogxK
U2 - 10.3389/fncir.2019.00036
DO - 10.3389/fncir.2019.00036
M3 - 文章
C2 - 31156400
AN - SCOPUS:85066983254
SN - 1662-5110
VL - 13
JO - Frontiers in Neural Circuits
JF - Frontiers in Neural Circuits
M1 - 36
ER -