Synaptic modifications driven by spike-timing-dependent plasticity in weakly coupled bursting neurons

Jian Fang Zhou, Wu Jie Yuan, Debao Chen, Bing Hong Wang, Zhao Zhou, Stefano Boccaletti, Zhen Wang

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4 引用 (Scopus)

摘要

In the course of development, sleep, or mental disorders, certain neurons in the brain display spontaneous spike-burst activity. The synaptic plasticity evoked by such activity is here studied in the presence of spike-timing-dependent plasticity (STDP). In two chemically coupled bursting model neurons, the spike-burst activity can translate the STDP related to pre- and postsynaptic spike activity into burst-timing-dependent plasticity (BTDP), based on the timing of bursts of pre- and postsynaptic neurons. The resulting BTDP exhibits exponential decays with the same time scales as those of STDP. In weakly coupled bursting neuron networks, the synaptic modification driven by the spike-burst activity obeys a power-law distribution. The model can also produce a power-law distribution of synaptic weights. Here, the considered bursting behavior is made of stereotypical groups of spikes, and bursting is evenly spaced by long intervals.

源语言英语
文章编号032419
期刊Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
99
3
DOI
出版状态已出版 - 26 3月 2019

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