TY - JOUR
T1 - Synaptic modifications driven by spike-timing-dependent plasticity in weakly coupled bursting neurons
AU - Zhou, Jian Fang
AU - Yuan, Wu Jie
AU - Chen, Debao
AU - Wang, Bing Hong
AU - Zhou, Zhao
AU - Boccaletti, Stefano
AU - Wang, Zhen
N1 - Publisher Copyright:
© 2019 American Physical Society.
PY - 2019/3/26
Y1 - 2019/3/26
N2 - In the course of development, sleep, or mental disorders, certain neurons in the brain display spontaneous spike-burst activity. The synaptic plasticity evoked by such activity is here studied in the presence of spike-timing-dependent plasticity (STDP). In two chemically coupled bursting model neurons, the spike-burst activity can translate the STDP related to pre- and postsynaptic spike activity into burst-timing-dependent plasticity (BTDP), based on the timing of bursts of pre- and postsynaptic neurons. The resulting BTDP exhibits exponential decays with the same time scales as those of STDP. In weakly coupled bursting neuron networks, the synaptic modification driven by the spike-burst activity obeys a power-law distribution. The model can also produce a power-law distribution of synaptic weights. Here, the considered bursting behavior is made of stereotypical groups of spikes, and bursting is evenly spaced by long intervals.
AB - In the course of development, sleep, or mental disorders, certain neurons in the brain display spontaneous spike-burst activity. The synaptic plasticity evoked by such activity is here studied in the presence of spike-timing-dependent plasticity (STDP). In two chemically coupled bursting model neurons, the spike-burst activity can translate the STDP related to pre- and postsynaptic spike activity into burst-timing-dependent plasticity (BTDP), based on the timing of bursts of pre- and postsynaptic neurons. The resulting BTDP exhibits exponential decays with the same time scales as those of STDP. In weakly coupled bursting neuron networks, the synaptic modification driven by the spike-burst activity obeys a power-law distribution. The model can also produce a power-law distribution of synaptic weights. Here, the considered bursting behavior is made of stereotypical groups of spikes, and bursting is evenly spaced by long intervals.
UR - http://www.scopus.com/inward/record.url?scp=85064071129&partnerID=8YFLogxK
U2 - 10.1103/PhysRevE.99.032419
DO - 10.1103/PhysRevE.99.032419
M3 - 文章
C2 - 30999534
AN - SCOPUS:85064071129
SN - 1539-3755
VL - 99
JO - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
JF - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
IS - 3
M1 - 032419
ER -