Preparation of collagen/hydroxyapatite composite coating on porous Titanium substrate and its cellular response

Ting Li, Jin Shan Li, Hong Chao Kou, Fu Ping Li, Ting Li Lu

科研成果: 书/报告/会议事项章节会议稿件同行评审

2 引用 (Scopus)

摘要

In this article, the layered deposition method is adopted to prepare the collagen/hydroxyapatite(COL/HA) composite coating. The morphology and elements of the COL/HA composite coating are observed using a scanning electron microscope(SEM)with an energy dispersive spectrometer(EDS), the optical density(O.D.) values are obtained by MTT assay to assess the cellular viabilityof composite coating. The experimental results showed that the addition of collagen not only improve the bonding strength of composite coating and porous titanium substrate, but also combine the osteoconduction of inorganic coating HA and the osteoinduction of organic coating COL, effectively enhance the cellular adhesion, proliferation and differentiation. The cellular viability cultured in COL/HA composite coating is much higher than the pure HA modified coating.

源语言英语
主期刊名Advanced Functional Materials
编辑Yafang Han, Zhongwei Gu, Qiang Fu
出版商Trans Tech Publications Ltd
429-433
页数5
ISBN(电子版)9783038353942
DOI
出版状态已出版 - 2015
活动Chinese Materials Congress, CMC 2014 - Chengdu, 中国
期限: 4 7月 20147 7月 2014

出版系列

姓名Materials Science Forum
815
ISSN(印刷版)0255-5476
ISSN(电子版)1662-9752

会议

会议Chinese Materials Congress, CMC 2014
国家/地区中国
Chengdu
时期4/07/147/07/14

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