TY - JOUR
T1 - Natural Nanoclay-Based Silver-Phosphomolybdic Acid Composite with a Dual Antimicrobial Effect
AU - Novikov, Andrei A.
AU - Sayfutdinova, Adeliya R.
AU - Gorbachevskii, Maksim V.
AU - Filatova, Sofya V.
AU - Filimonova, Alla V.
AU - Rodrigues-Filho, Ubirajara Pereira
AU - Fu, Ye
AU - Wang, Wencai
AU - Wang, Hongqiang
AU - Vinokurov, Vladimir A.
AU - Shchukin, Dmitry G.
N1 - Publisher Copyright:
© 2022 The Authors. Published by American Chemical Society
PY - 2022/3/1
Y1 - 2022/3/1
N2 - The problem of microbial growth on various surfaces has increased concern in society in the context of antibiotic misuse and the spreading of hospital infections. Thus, the development of new, antibiotic-free antibacterial strategies is required to combat bacteria resistant to usual antibiotic treatments. This work reports a new method for producing an antibiotic-free antibacterial halloysite-based nanocomposite with silver nanoparticles and phosphomolybdic acid as biocides, which can be used as components of smart antimicrobial coatings. The composite was characterized by using energy-dispersive X-ray fluorescence spectroscopy and transmission electron microscopy. The release of phosphomolybdic acid from the nanocomposite was studied by using UV-vis spectroscopy. It was shown that the antibiotic-free nanocomposite consisting of halloysite nanotubes decorated with silver nanoparticles loaded with phosphomolybdic acid and treated with calcium chloride possesses broad antibacterial properties, including the complete growth inhibition of Staphylococcus aureus and Pseudomonas aeruginosa bacteria at a 0.5 g × L-1 concentration and Acinetobacter baumannii at a 0.25 g × L-1 concentration.
AB - The problem of microbial growth on various surfaces has increased concern in society in the context of antibiotic misuse and the spreading of hospital infections. Thus, the development of new, antibiotic-free antibacterial strategies is required to combat bacteria resistant to usual antibiotic treatments. This work reports a new method for producing an antibiotic-free antibacterial halloysite-based nanocomposite with silver nanoparticles and phosphomolybdic acid as biocides, which can be used as components of smart antimicrobial coatings. The composite was characterized by using energy-dispersive X-ray fluorescence spectroscopy and transmission electron microscopy. The release of phosphomolybdic acid from the nanocomposite was studied by using UV-vis spectroscopy. It was shown that the antibiotic-free nanocomposite consisting of halloysite nanotubes decorated with silver nanoparticles loaded with phosphomolybdic acid and treated with calcium chloride possesses broad antibacterial properties, including the complete growth inhibition of Staphylococcus aureus and Pseudomonas aeruginosa bacteria at a 0.5 g × L-1 concentration and Acinetobacter baumannii at a 0.25 g × L-1 concentration.
UR - http://www.scopus.com/inward/record.url?scp=85125122883&partnerID=8YFLogxK
U2 - 10.1021/acsomega.1c06283
DO - 10.1021/acsomega.1c06283
M3 - 文章
AN - SCOPUS:85125122883
SN - 2470-1343
VL - 7
SP - 6728
EP - 6736
JO - ACS Omega
JF - ACS Omega
IS - 8
ER -