TY - JOUR
T1 - Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation
AU - Wang, Kun
AU - Shen, Yanjun
AU - Yang, Yongzhi
AU - Gan, Xiaoni
AU - Liu, Guichun
AU - Hu, Kuang
AU - Li, Yongxin
AU - Gao, Zhaoming
AU - Zhu, Li
AU - Yan, Guoyong
AU - He, Lisheng
AU - Shan, Xiujuan
AU - Yang, Liandong
AU - Lu, Suxiang
AU - Zeng, Honghui
AU - Pan, Xiangyu
AU - Liu, Chang
AU - Yuan, Yuan
AU - Feng, Chenguang
AU - Xu, Wenjie
AU - Zhu, Chenglong
AU - Xiao, Wuhan
AU - Dong, Yang
AU - Wang, Wen
AU - Qiu, Qiang
AU - He, Shunping
N1 - Publisher Copyright:
© 2019, The Author(s), under exclusive licence to Springer Nature Limited.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - It is largely unknown how living organisms—especially vertebrates—survive and thrive in the coldness, darkness and high pressures of the hadal zone. Here, we describe the unique morphology and genome of Pseudoliparis swirei—a recently described snailfish species living below a depth of 6,000 m in the Mariana Trench. Unlike closely related shallow sea species, P. swirei has transparent, unpigmented skin and scales, thin and incompletely ossified bones, an inflated stomach and a non-closed skull. Phylogenetic analyses show that P. swirei diverged from a close relative living near the sea surface about 20 million years ago and has abundant genetic diversity. Genomic analyses reveal that: (1) the bone Gla protein (bglap) gene has a frameshift mutation that may cause early termination of cartilage calcification; (2) cell membrane fluidity and transport protein activity in P. swirei may have been enhanced by changes in protein sequences and gene expansion; and (3) the stability of its proteins may have been increased by critical mutations in the trimethylamine N-oxide-synthesizing enzyme and hsp90 chaperone protein. Our results provide insights into the morphological, physiological and molecular evolution of hadal vertebrates.
AB - It is largely unknown how living organisms—especially vertebrates—survive and thrive in the coldness, darkness and high pressures of the hadal zone. Here, we describe the unique morphology and genome of Pseudoliparis swirei—a recently described snailfish species living below a depth of 6,000 m in the Mariana Trench. Unlike closely related shallow sea species, P. swirei has transparent, unpigmented skin and scales, thin and incompletely ossified bones, an inflated stomach and a non-closed skull. Phylogenetic analyses show that P. swirei diverged from a close relative living near the sea surface about 20 million years ago and has abundant genetic diversity. Genomic analyses reveal that: (1) the bone Gla protein (bglap) gene has a frameshift mutation that may cause early termination of cartilage calcification; (2) cell membrane fluidity and transport protein activity in P. swirei may have been enhanced by changes in protein sequences and gene expansion; and (3) the stability of its proteins may have been increased by critical mutations in the trimethylamine N-oxide-synthesizing enzyme and hsp90 chaperone protein. Our results provide insights into the morphological, physiological and molecular evolution of hadal vertebrates.
UR - http://www.scopus.com/inward/record.url?scp=85064534085&partnerID=8YFLogxK
U2 - 10.1038/s41559-019-0864-8
DO - 10.1038/s41559-019-0864-8
M3 - 文章
C2 - 30988486
AN - SCOPUS:85064534085
SN - 2397-334X
VL - 3
SP - 823
EP - 833
JO - Nature Ecology and Evolution
JF - Nature Ecology and Evolution
IS - 5
ER -