Joint analysis of cortical folding pattern, thickness and fiber density using structural and DTI data

Yixuan Yuan, Lei Guo, Gang Li, Tuo Zhang, Xintao Hu, Tianming Liu

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Cortical folding is an essential geometric characteristic of the human cerebral cortex. The cortical folding pattern conveys important information about brain architecture and function. Cortical thickness is another important morphological feature that reflects the size, density, and arrangement of cells in the cortex. Meanwhile, cortical regions are connected by short-distance or long-distance white matter fibers and neuroscience research reports that axongenesis and corticogensis are closely associated. This paper focuses on applying in-house developed tools to quantify the cortical folding patterns, thickness and fiber density using structural and diffusion tensor imaging (DTI) data and analyzing their associations in normal brains. Our experimental results show that cortical folding patterns are highly correlated with cortical thickness and fiber density distributions on the cortex. This result can potentially provide new clues regarding the architecture, function and development of the human brain.

源语言英语
主期刊名2010 7th IEEE International Symposium on Biomedical Imaging
主期刊副标题From Nano to Macro, ISBI 2010 - Proceedings
404-407
页数4
DOI
出版状态已出版 - 2010
活动7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Rotterdam, 荷兰
期限: 14 4月 201017 4月 2010

出版系列

姓名2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings

会议

会议7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
国家/地区荷兰
Rotterdam
时期14/04/1017/04/10

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