Inner salt-shaped small molecular photosensitizer with extremely enhanced two-photon absorption for mitochondrial-targeted photodynamic therapy

Wenbo Hu, Tingchao He, Rongcui Jiang, Jun Yin, Lin Li, Xiaomei Lu, Hui Zhao, Lei Zhang, Ling Huang, Handong Sun, Wei Huang, Quli Fan

科研成果: 期刊稿件文章同行评审

47 引用 (Scopus)

摘要

Herein, we experimentally and theoretically demonstrate an unprecedentedly enhanced two-photon absorption in a small organic molecule by a simple introduction of an inner salt-shaped structure. Moreover, such an inner salt-shaped small molecule also exhibits superior singlet oxygen quantum yield and fascinating structure-inherent mitochondrial-targeting ability for highly efficient two-photon photodynamic therapy via a mitochondrial apoptosis pathway.

源语言英语
页(从-至)1680-1683
页数4
期刊Chemical Communications
53
10
DOI
出版状态已出版 - 2017
已对外发布

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