Immobilization of lipase on iron oxide organic/inorganic hybrid particles: A review article

In last few decades the demand of lipase has been dramatically increase due to its useful use in numbers of biochemical industries. Varieties of natural and synthetic carriers and methodologies have been used to improve lipase activities by the process of immobilization in order to enhance its activities in term of its resistance to high temperature, pH and to increase its reusibity and storage capacity. Due to the expensive nature the recycling of the lipase has been the target of the researchers to decrease its cost in the industrial process. Magnetic iron oxide organic/inorganic hybrid nanoparticles as a support have been mostly used in the lipase immobilization due its large surface area, less toxicity, bio compatibility, easily functionalization, separation avoiding long time consuming process like filtration and centrifuging.