TY - JOUR
T1 - Extinction effects of multiplicative non-gaussian lévy noise in a tumor growth system with immunization
AU - Hao, Meng Li
AU - Xu, Wei
AU - Li, Dong Xi
AU - Liu, Di
PY - 2014/5
Y1 - 2014/5
N2 - The extinction phenomenon induced by multiplicative non-Gaussian Lévy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in terms of a stochastic differential equation with multiplicative noise. By means of the theory of the infinitesimal generator of Hunt processes, the escape probability, which is used to measure the noise-induced extinction probability of tumor cells, is explicitly expressed as a function of initial tumor cell density, stability index and noise intensity. Based on the numerical calculations, it is found that for different initial densities of tumor cells, noise parameters play opposite roles on the escape probability. The optimally selected values of the multiplicative noise intensity and the stability index are found to maximize the escape probability.
AB - The extinction phenomenon induced by multiplicative non-Gaussian Lévy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in terms of a stochastic differential equation with multiplicative noise. By means of the theory of the infinitesimal generator of Hunt processes, the escape probability, which is used to measure the noise-induced extinction probability of tumor cells, is explicitly expressed as a function of initial tumor cell density, stability index and noise intensity. Based on the numerical calculations, it is found that for different initial densities of tumor cells, noise parameters play opposite roles on the escape probability. The optimally selected values of the multiplicative noise intensity and the stability index are found to maximize the escape probability.
KW - model of tumor growth
KW - noise-induced extinction probability
KW - non-Gaussian Lévy motion
KW - stochastic immune rate
UR - http://www.scopus.com/inward/record.url?scp=84900511440&partnerID=8YFLogxK
U2 - 10.1088/0253-6102/61/5/05
DO - 10.1088/0253-6102/61/5/05
M3 - 文章
AN - SCOPUS:84900511440
SN - 0253-6102
VL - 61
SP - 571
EP - 577
JO - Communications in Theoretical Physics
JF - Communications in Theoretical Physics
IS - 5
ER -