TY - JOUR
T1 - Development of a ground-based simulated experimental platform for gravitational biology
AU - Qian, Airong
AU - Yin, Dachuan
AU - Yang, Pengfei
AU - Jia, Bin
AU - Zhang, Wei
AU - Shang, Peng
PY - 2009/4
Y1 - 2009/4
N2 - The purpose of this study is to develop a ground-based experimental platform which can provide a long-term, persistent, and stable weightless environment to provide technical support for the fundamental study of space life sciences. The platform included a superconducting magnet which can generate a large gradient high magnetic field, temperature control system, object stage, observing system, and gas control system. The platform can accurately measure and control comprehensive parameters, such as temperature, humidity, sample location, gravity level, and magnetic induction intensity. The biological experiment by means of the platform indicated that diamagnetic levitation affected cell morphology but had nonlethal effects on cell growth, which is consistent with the results of spaceflight. It suggests that the platform can meet the need of the simulated experimental conditions for gravitational biology research from molecule, cell, tissue, and organ to model animal.
AB - The purpose of this study is to develop a ground-based experimental platform which can provide a long-term, persistent, and stable weightless environment to provide technical support for the fundamental study of space life sciences. The platform included a superconducting magnet which can generate a large gradient high magnetic field, temperature control system, object stage, observing system, and gas control system. The platform can accurately measure and control comprehensive parameters, such as temperature, humidity, sample location, gravity level, and magnetic induction intensity. The biological experiment by means of the platform indicated that diamagnetic levitation affected cell morphology but had nonlethal effects on cell growth, which is consistent with the results of spaceflight. It suggests that the platform can meet the need of the simulated experimental conditions for gravitational biology research from molecule, cell, tissue, and organ to model animal.
KW - Diamagnetic levitation
KW - Large gradient high magnetic field
KW - Simulated weightlessness
KW - Superconducting magnet
UR - http://www.scopus.com/inward/record.url?scp=64049089023&partnerID=8YFLogxK
U2 - 10.1109/TASC.2009.2012422
DO - 10.1109/TASC.2009.2012422
M3 - 文章
AN - SCOPUS:64049089023
SN - 1051-8223
VL - 19
SP - 42
EP - 46
JO - IEEE Transactions on Applied Superconductivity
JF - IEEE Transactions on Applied Superconductivity
IS - 2
M1 - 4768622
ER -