TY - JOUR
T1 - Detection of functional connectivity in the brain during visuo-guided grip force tracking tasks
T2 - A functional near-infrared spectroscopy study
AU - Zheng, Xinyi
AU - Luo, Jie
AU - Deng, Lingyun
AU - Li, Bing
AU - Li, Le
AU - Huang, Dong Feng
AU - Song, Rong
N1 - Publisher Copyright:
© 2020 Wiley Periodicals LLC
PY - 2021/4
Y1 - 2021/4
N2 - The functional connectivity (FC) between multiple brain regions during tasks is currently gradually being explored with functional near-infrared spectroscopy (fNIRS). However, the FC present during grip force tracking tasks performed under visual feedback remains unclear. In the present study, we used fNIRS to measure brain activity during resting states and grip force tracking tasks at 25%, 50%, and 75% of maximum voluntary contraction (MVC) in 11 healthy subjects, and the activity was measured from four target brain regions: the left prefrontal cortex (lPFC), right prefrontal cortex (rPFC), left sensorimotor cortex (lSMC), and right sensorimotor cortex (rSMC). We determined the FC between these regions utilizing three different methods: Pearson's correlation method, partial correlation method, and a pairwise maximum entropy model (MEM). The results showed that the FC of lSMC-rSMC and lPFC-rPFC (interhemispheric homologous pairs) were significantly stronger than those of other brain region pairs. Moreover, FC of lPFC-rPFC was strengthened during the 75% MVC task compared to the other task states and the resting states. The FC of lSMC-lPFC and rSMC-rPFC (intrahemispheric region pairs) strengthened with a higher task load. The results provided new insights into the FC between brain regions during visuo-guided grip force tracking tasks.
AB - The functional connectivity (FC) between multiple brain regions during tasks is currently gradually being explored with functional near-infrared spectroscopy (fNIRS). However, the FC present during grip force tracking tasks performed under visual feedback remains unclear. In the present study, we used fNIRS to measure brain activity during resting states and grip force tracking tasks at 25%, 50%, and 75% of maximum voluntary contraction (MVC) in 11 healthy subjects, and the activity was measured from four target brain regions: the left prefrontal cortex (lPFC), right prefrontal cortex (rPFC), left sensorimotor cortex (lSMC), and right sensorimotor cortex (rSMC). We determined the FC between these regions utilizing three different methods: Pearson's correlation method, partial correlation method, and a pairwise maximum entropy model (MEM). The results showed that the FC of lSMC-rSMC and lPFC-rPFC (interhemispheric homologous pairs) were significantly stronger than those of other brain region pairs. Moreover, FC of lPFC-rPFC was strengthened during the 75% MVC task compared to the other task states and the resting states. The FC of lSMC-lPFC and rSMC-rPFC (intrahemispheric region pairs) strengthened with a higher task load. The results provided new insights into the FC between brain regions during visuo-guided grip force tracking tasks.
KW - functional connectivity
KW - functional near-infrared spectroscopy (fNIRS)
KW - grip force tracking
KW - pairwise MEM
KW - partial correlation
UR - http://www.scopus.com/inward/record.url?scp=85097955853&partnerID=8YFLogxK
U2 - 10.1002/jnr.24769
DO - 10.1002/jnr.24769
M3 - 文章
C2 - 33368535
AN - SCOPUS:85097955853
SN - 0360-4012
VL - 99
SP - 1108
EP - 1119
JO - Journal of Neuroscience Research
JF - Journal of Neuroscience Research
IS - 4
ER -