Cationic peptidopolysaccharides show excellent broad-spectrum antimicrobial activities and high selectivity

Peng Li, Chuncai Zhou, Shahrzad Rayatpisheh, Kai Ye, Yin Fun Poon, Paula T. Hammond, Hongwei Duan, Mary B. Chan-Park

科研成果: 期刊稿件文章同行评审

245 引用 (Scopus)

摘要

Facilely synthesized cationic peptidopolysaccharides, which have a bacterial peptidoglycan-mimetic structure, show outstanding broad-spectrum activities against clinically significant bacteria and fungi and low mammalian cytotoxicity. Their structural affinity with microbial cell-wall constituents promotes penetration to reach the cytoplasmic membrane resulting in excellent antimicrobial activity and high selectivity.

源语言英语
页(从-至)4130-4137
页数8
期刊Advanced Materials
24
30
DOI
出版状态已出版 - 8 8月 2012
已对外发布

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