Angular resolution enhancement of diffusion MRI data using inter-subject information transfer

Geng Chen, Pei Zhang, Ke Li, Chong Yaw Wee, Yafeng Wu, Dinggang Shen, Pew Thian Yap

科研成果: 书/报告/会议事项章节会议稿件同行评审

2 引用 (Scopus)

摘要

Diffusion magnetic resonance imaging is widely used to investigate diffusion patterns of water molecules in the human brain. It provides information that is useful for tracing axonal bundles and inferring brain connectivity. Diffusion axonal tracing, namely tractography, relies on local directional information provided by the orientation distribution functions (ODFs) estimated at each voxel. To accurately estimate ODFs, data of good signal-to-noise ratio and sufficient angular samples are desired, but unfortunately, are not always practically available. In this paper, we propose to improve ODF estimation by using inter-subject correlation. Specifically, diffusion-weighted images acquired from different subjects, when transformed to the space of a target subject, can not only provide signal denoising with additional information, but also drastically increase the number of angular samples for better ODF estimation. This is largely because of the incoherence of the angular samples generated when the diffusion signals are reoriented and warped to the target space. Experiments on both synthetic data and real data show that our method can reduce noise-induced artifacts, such as spurious ODF peaks, and yield more coherent orientations.

源语言英语
主期刊名Computational Diffusion MRI - MICCAI Workshop, 2015
编辑Yogesh Rathi, Andrea Fuster, Aurobrata Ghosh, Enrico Kaden, Marco Reisert
出版商Springer Heidelberg
145-157
页数13
ISBN(印刷版)9783319285863
DOI
出版状态已出版 - 2016
活动Workshop on Computational Diffusion MRI, MICCAI 2015 - Munich, 德国
期限: 9 10月 20159 10月 2015

出版系列

姓名Mathematics and Visualization
none
ISSN(印刷版)1612-3786
ISSN(电子版)2197-666X

会议

会议Workshop on Computational Diffusion MRI, MICCAI 2015
国家/地区德国
Munich
时期9/10/159/10/15

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