3-Substituted BINOL schiff bases and their reductive products for catalytic asymmetric addition of diethylzinc to aldehydes

Bing Liu, Zhi Bing Dong, Cao Fang, Hai Bin Song, Jin Shan Li

科研成果: 期刊稿件文章同行评审

8 引用 (Scopus)

摘要

Three new chiral 3-substituted BINOL Schiff bases and their reductive 3-arylaminomethylBINOL products have been synthesized and used for the asymmetric addition reaction of diethylzinc to aldehydes in the presence of titanium tetraisopropoxide. The reaction provided optically active secondary alcohols in high yield (86-100%) and good enantioselectivity (up to 92% ee).

源语言英语
页(从-至)828-832
页数5
期刊Chirality
20
7
DOI
出版状态已出版 - 7月 2008
已对外发布

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