TPRO: Text-Prompting-Based Weakly Supervised Histopathology Tissue Segmentation

Shaoteng Zhang, Jianpeng Zhang, Yutong Xie, Yong Xia

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

11 Scopus citations

Abstract

Most existing weakly-supervised segmentation methods rely on class activation maps (CAM) to generate pseudo-labels for training segmentation models. However, CAM has been criticized for highlighting only the most discriminative parts of the object, leading to poor quality of pseudo-labels. Although some recent methods have attempted to extend CAM to cover more areas, the fundamental problem still needs to be solved. We believe this problem is due to the huge gap between image-level labels and pixel-level predictions and that additional information must be introduced to address this issue. Thus, we propose a text-prompting-based weakly supervised segmentation method (TPRO), which uses text to introduce additional information. TPRO employs a vision and label encoder to generate a similarity map for each image, which serves as our localization map. Pathological knowledge is gathered from the internet and embedded as knowledge features, which are used to guide the image features through a knowledge attention module. Additionally, we employ a deep supervision strategy to utilize the network’s shallow information fully. Our approach outperforms other weakly supervised segmentation methods on benchmark datasets LUAD-HistoSeg and BCSS-WSSS datasets, setting a new state of the art. Code is available at: https://github.com/zhangst431/TPRO.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2023 - 26th International Conference, Proceedings
EditorsHayit Greenspan, Hayit Greenspan, Anant Madabhushi, Parvin Mousavi, Septimiu Salcudean, James Duncan, Tanveer Syeda-Mahmood, Russell Taylor
PublisherSpringer Science and Business Media Deutschland GmbH
Pages109-118
Number of pages10
ISBN (Print)9783031439063
DOIs
StatePublished - 2023
Event26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023 - Vancouver, Canada
Duration: 8 Oct 202312 Oct 2023

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume14220 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference26th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2023
Country/TerritoryCanada
CityVancouver
Period8/10/2312/10/23

Keywords

  • Histopathology Tissue Segmentation
  • Vision-Language
  • Weakly-Supervised Semantic Segmentation

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