Theoretical study on single-molecule spectroscopy

Guang Cun Shan, Wei Huang

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The photon-by-photon approach for single molecule spectroscopy experiments utilizes the information carried by each detected photon and allows the measurements of conformational fluctuation with time resolution on a vast range of time scales, where each photon represents a data point. Here, we theoretically simulate the photon emission dynamics of a single molecule spectroscopy using the kinetic Monte Carlo algorithm to understand the underlying complex photon dynamic process of a single molecule. In addition, by following the molecular process in real time, the mechanism of complex biochemical reactions can be revealed. We hope that this theoretical study will serve as an introduction and a guideline into this exciting new field.

Original languageEnglish
Pages (from-to)405-411
Number of pages7
JournalFrontiers of Physics in China
Volume1
Issue number4
DOIs
StatePublished - Dec 2006
Externally publishedYes

Keywords

  • Conformation
  • Dynamical process
  • Kinetic Monte Carlo
  • Nanotechnology
  • Single-molecule spectroscopy (SMS)

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