The origin of new genes: Glimpses from the young and old

Manyuan Long; Esther Betrán; Kevin Thornton; Wen Wang

doi:10.1038/nrg1204

The origin of new genes: Glimpses from the young and old

Manyuan Long, Esther Betrán, Kevin Thornton, Wen Wang

Research output: Contribution to journal › Review article › peer-review

729 Scopus citations

Abstract

Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. However, there has been little opportunity to explore how genes with new functions originate and evolve. The study of ancient genes has highlighted the antiquity and general importance of some mechanisms of gene origination, and recent observations of young genes at early stages in their evolution have unveiled unexpected molecular and evolutionary processes.

Original language	English
Pages (from-to)	865-875
Number of pages	11
Journal	Nature Reviews Genetics
Volume	4
Issue number	11
DOIs	https://doi.org/10.1038/nrg1204
State	Published - Nov 2003
Externally published	Yes

Access to Document

10.1038/nrg1204

Cite this

@article{ff95c4468e8b4937bd429c4f4c0a304c,

title = "The origin of new genes: Glimpses from the young and old",

abstract = "Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. However, there has been little opportunity to explore how genes with new functions originate and evolve. The study of ancient genes has highlighted the antiquity and general importance of some mechanisms of gene origination, and recent observations of young genes at early stages in their evolution have unveiled unexpected molecular and evolutionary processes.",

author = "Manyuan Long and Esther Betr{\'a}n and Kevin Thornton and Wen Wang",

year = "2003",

month = nov,

doi = "10.1038/nrg1204",

language = "英语",

volume = "4",

pages = "865--875",

journal = "Nature Reviews Genetics",

issn = "1471-0056",

publisher = "Nature Research",

number = "11",

}

TY - JOUR

T1 - The origin of new genes

T2 - Glimpses from the young and old

AU - Long, Manyuan

AU - Betrán, Esther

AU - Thornton, Kevin

AU - Wang, Wen

PY - 2003/11

Y1 - 2003/11

N2 - Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. However, there has been little opportunity to explore how genes with new functions originate and evolve. The study of ancient genes has highlighted the antiquity and general importance of some mechanisms of gene origination, and recent observations of young genes at early stages in their evolution have unveiled unexpected molecular and evolutionary processes.

AB - Genome data have revealed great variation in the numbers of genes in different organisms, which indicates that there is a fundamental process of genome evolution: the origin of new genes. However, there has been little opportunity to explore how genes with new functions originate and evolve. The study of ancient genes has highlighted the antiquity and general importance of some mechanisms of gene origination, and recent observations of young genes at early stages in their evolution have unveiled unexpected molecular and evolutionary processes.

UR - http://www.scopus.com/inward/record.url?scp=0242354129&partnerID=8YFLogxK

U2 - 10.1038/nrg1204

DO - 10.1038/nrg1204

M3 - 文献综述

C2 - 14634634

AN - SCOPUS:0242354129

SN - 1471-0056

VL - 4

SP - 865

EP - 875

JO - Nature Reviews Genetics

JF - Nature Reviews Genetics

IS - 11

ER -

The origin of new genes: Glimpses from the young and old

Abstract

Access to Document

Other files and links

Fingerprint

Cite this