TY - JOUR
T1 - Synthesis of 3 or 3,3′-substituted BINOL ligands and their application in the asymmetric addition of diethylzinc to aromatic aldehydes
AU - Guo, Qun Sheng
AU - Liu, Bing
AU - Lu, Yong Na
AU - Jiang, Fu Yong
AU - Song, Hai Bin
AU - Li, Jin Shan
PY - 2005/11/14
Y1 - 2005/11/14
N2 - Three new substituted BINOL ligands (R)-3-[4,6-bis(dimethylamino)-1,3,5- triazin-2-yl]-1,1′-bi-2-naphthol (R)-1, (R)-3,3′-bis[4,6- bis(dimethylamino)-1,3,5-triazin-2-yl]-1,1′-bi-2-naphthol (R)-2 and 2,4-bis(2,2′-dihydroxy-1,1′-binaphthalen-3-yl)-6-(p-tolyl)-1,3, 5-triazine (R,R)-3 have been obtained by directed ortho-lithiation or Suzuki cross-coupling process. Ligand (R)-1 shows improved catalytic properties for the asymmetric diethylzinc addition to aromatic aldehydes.
AB - Three new substituted BINOL ligands (R)-3-[4,6-bis(dimethylamino)-1,3,5- triazin-2-yl]-1,1′-bi-2-naphthol (R)-1, (R)-3,3′-bis[4,6- bis(dimethylamino)-1,3,5-triazin-2-yl]-1,1′-bi-2-naphthol (R)-2 and 2,4-bis(2,2′-dihydroxy-1,1′-binaphthalen-3-yl)-6-(p-tolyl)-1,3, 5-triazine (R,R)-3 have been obtained by directed ortho-lithiation or Suzuki cross-coupling process. Ligand (R)-1 shows improved catalytic properties for the asymmetric diethylzinc addition to aromatic aldehydes.
UR - http://www.scopus.com/inward/record.url?scp=27944454827&partnerID=8YFLogxK
U2 - 10.1016/j.tetasy.2005.09.018
DO - 10.1016/j.tetasy.2005.09.018
M3 - 文章
AN - SCOPUS:27944454827
SN - 0957-4166
VL - 16
SP - 3667
EP - 3671
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 22
ER -