Synthesis and application of water-soluble conjugated glycopolymer

Pengfei Sun, Huanzhi Hou, Quli Fan, Wei Huang

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Water-soluble conjugated polymers (WSCPs) have been applied to a wide range of fields such as chemical sensing, bio-sensing and bio-imaging. The advantages of WSCPs for these applications include their high brightness, good photo-stability, structure variety and sufficient solubility in aqueous solution. WSCPs are usually decorated with water-soluble ionic groups or polymers on their sides or end groups. Sugars are a kind of biomolecules existing naturally and most of them have the features of water-solubility, therefore in recent years researchers have introduced sugar compounds into conjugated polymers leading to water-soluble conjugated glycopolymers with the biological properties of carbonhydrates. In this review, we summarize the recent development in the synthesis of water-soluble conjugated glycopolymers and their applications in terms of lectin-sensing, bacteria-sensing and live-cell imaging. Finally, we point out the peculiarity, developing trend and the challenges of water-soluble conjugated glycopolymers.

Original languageEnglish
Pages (from-to)1489-1500
Number of pages12
JournalProgress in Chemistry
Volume28
Issue number10
DOIs
StatePublished - 24 Oct 2016
Externally publishedYes

Keywords

  • Fluorescence detection
  • Glycopolymer
  • Lectin
  • Water-soluble conjugated polymers

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