TY - JOUR
T1 - Structural features and biological activities of the polysaccharides from Astragalus membranaceus
AU - Jin, Mingliang
AU - Zhao, Ke
AU - Huang, Qingsheng
AU - Shang, Peng
PY - 2014/3
Y1 - 2014/3
N2 - Recently, a great deal of interest has been developed to isolate and investigate novel bioactive components with health benefit effects from natural resources. The dried root of Astragalus membranaceus, one of the most popular health-promoting herbal medicines, has been used historically as an immunomodulating agent for the treatment of common cold, diarrhea, fatigue and anorexia for more than 2000 years. Modern phytochemistry and pharmacological experiments have proved that polysaccharide is one of the major active ingredients in the root of A. membranaceus with various important bioactivities, such as immunomodulation, antioxidant, antitumor, anti-diabetes, antiviral, hepatoprotection, anti-inflammation, anti-atherosclerosis, hematopoiesis and neuroprotection. The aim of the present review is to summarize previous and current references and give a comprehensive summary regarding the structural features and biological activities of A. membranaceus polysaccharides in order to provide new insight for further development of these macromolecules.
AB - Recently, a great deal of interest has been developed to isolate and investigate novel bioactive components with health benefit effects from natural resources. The dried root of Astragalus membranaceus, one of the most popular health-promoting herbal medicines, has been used historically as an immunomodulating agent for the treatment of common cold, diarrhea, fatigue and anorexia for more than 2000 years. Modern phytochemistry and pharmacological experiments have proved that polysaccharide is one of the major active ingredients in the root of A. membranaceus with various important bioactivities, such as immunomodulation, antioxidant, antitumor, anti-diabetes, antiviral, hepatoprotection, anti-inflammation, anti-atherosclerosis, hematopoiesis and neuroprotection. The aim of the present review is to summarize previous and current references and give a comprehensive summary regarding the structural features and biological activities of A. membranaceus polysaccharides in order to provide new insight for further development of these macromolecules.
KW - Astragalus membranaceus
KW - Bioactivities
KW - Polysaccharide
UR - http://www.scopus.com/inward/record.url?scp=84891103186&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2013.12.002
DO - 10.1016/j.ijbiomac.2013.12.002
M3 - 文献综述
C2 - 24325861
AN - SCOPUS:84891103186
SN - 0141-8130
VL - 64
SP - 257
EP - 266
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -
