Species-Preserved Structural Connections Revealed by Sparse Tensor CCA

Zhibin He, Ying Huang, Tianming Liu, Lei Guo, Lei Du, Tuo Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Comparative evolution studies can advance the understating of the brain’s functional and structural mechanisms. Efforts have been denoted in the literature to identify structural common connectome preserved between a pair of species, such as macaques and humans. However, very few studies were reported to identify species-preserved structural connections systematically and simultaneously across more than two species at a connectome-scale. In this work, we used diffusion MRI (dMRI) and Brodmann areas as established tools to estimate the whole-brain connectome for three primates: macaque, chimpanzee and human. We designed a sparse tensor canonical correlation analysis (STCCA) algorithm to identify the connective components that are strongly correlated among the three species. Joint analysis of the components can help to identify the white matter pathways preserved among three species. These preserved connections are consistent with the existing neuroscience reports, demonstrating the effectiveness and promise of this framework.

Original languageEnglish
Title of host publicationMultimodal Brain Image Analysis and Mathematical Foundations of Computational Anatomy - 4th International Workshop, MBIA 2019, and 7th International Workshop, MFCA 2019, Held in Conjunction with MICCAI 2019, Proceedings
EditorsDajiang Zhu, Jingwen Yan, Heng Huang, Li Shen, Paul M. Thompson, Carl-Fredrik Westin, Xavier Pennec, Sarang Joshi, Mads Nielsen, Stefan Sommer, Tom Fletcher, Stanley Durrleman
PublisherSpringer
Pages49-56
Number of pages8
ISBN (Print)9783030332259
DOIs
StatePublished - 2019
Event4th International Workshop on Multimodal Brain Image Analysis, MBAI 2019, and the 7th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2019, held in conjunction with the 22nd International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2019 - Shenzhen, China
Duration: 17 Oct 201917 Oct 2019

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11846 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference4th International Workshop on Multimodal Brain Image Analysis, MBAI 2019, and the 7th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2019, held in conjunction with the 22nd International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2019
Country/TerritoryChina
CityShenzhen
Period17/10/1917/10/19

Keywords

  • Diffusion MRI
  • Large-scale connectome
  • Species comparison

Fingerprint

Dive into the research topics of 'Species-Preserved Structural Connections Revealed by Sparse Tensor CCA'. Together they form a unique fingerprint.

Cite this