Refractive index dependent real-time plasmonic nanoprobes on a single silver nanocube for ultrasensitive detection of the lung cancer-associated miRNAs

Lei Zhang, Ying Zhang, Yanling Hu, Quli Fan, Wenjing Yang, Anran Li, Shuzhou Li, Wei Huang, Lianhui Wang

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

We developed a novel method for the real-time monitoring of the delicate change in refractive index (RI) when DNA or RNA hybridize near a DNA-capped silver nanocube (AgNC) surface. This method offers an alternative platform in the quantitative analysis of the trace lung cancer-associated miRNAs in label-free detection.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalChemical Communications
Volume51
Issue number2
DOIs
StatePublished - 7 Jan 2015
Externally publishedYes

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